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Preheat oven to 350 degrees F (175 degrees C). Lightly grease a baking dish with cooking spray. Set aside.
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Bring a large pot of lightly salted water to a boil. Add spaghetti, and cook for 8 to 10 minutes or until al dente. Drain, reserving ½ cup pasta water. Toss cooked pasta with 1 tablespoon olive oil and set aside.
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Meanwhile, heat remaining ½ tablespoon oil in a large sauce pan over medium high heat. Add andouille sausage and cook until crispy, about 6-8 minutes. Using a slotted spoon, transfer the sausage to a paper towel lined plate and set aside.
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Add butter to the remaining oil in saucepan. Once butter is melted, add onions and cook for 5-7 minutes or until translucent. Add bell peppers and cook for 3-4 minutes or until soften. Add mushrooms and garlic and cook for 2-3 minutes.
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Stir in flour. Cook stirring constantly for 2-3 minutes. Stir in turkey broth. Cook, stirring occasionally, until mixture comes to a boil.
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Reduce heat to medium low and stir in milk, cream, 1 tablespoon Cajun seasoning, 1 cup Parmesan cheese, reserved pasta water, salt and black pepper.
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Continue stirring until sauce has thickened slightly. Once sauce has thickened, stir in peas, shredded turkey and pasta. Toss to combine. Pour pasta mixture into prepared baking dish.
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In a small bowl, stir together remaining Parmesan cheese and Panko bread crumbs, Sprinkle bread crumbs over pasta in baking dish. Top bread crumbs with remaining Cajun seasoning.
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Bake pasta in preheated 350 degrees F oven for 20-25 minutes or until bubbly and heated through.